Ivermectin
Ivermectin
I-Ivermectin iyimpushana emhlophe ecwebezelayo, ayinaphunga.Incibilika ngokukhululekile ku-methanol, i-ethanol, i-acetone, i-ethyl acetate, cishe ayincibiliki emanzini, kanye ne-hygroscopic kancane.Ivermectin iyi-semisynthetic macrolide multi-component antibiotic, equkethe ikakhulukazi ivermectin B1 (Bla + B1b) okuqukethwe hhayi ngaphansi kuka-95%, okuyinto Bla okuqukethwe hhayi ngaphansi kuka-85%.
Isimiso Semithi
I-Ivermectin inomphumela ovimbelayo okhethiwe, ngokubophezela ebudlelwaneni obuphezulu beziteshi ze-chloride ne-glutamate njenge-valve kumangqamuzana ezinzwa namaseli emisipha ezilwane ezingenazintambo, okuholela ekungeneni kolwelwesi lwamangqamuzana ku-chloride ions, kubangela hyperpolarization yamangqamuzana ezinzwa. noma amangqamuzana emisipha, futhi kubangela ukukhubazeka noma ukufa kwezimuncagazi.Iphinde ihlanganyele neziteshi ze-chloride zamanye ama-valve e-ligand, njenge-neurotransmitter g-aminobutyric acid (GABA).Ukukhethwa kwalo mkhiqizo kungenxa yokuthi ezinye izilwane ezincelisayo azinazo iziteshi ze-glutamate-chloride ku-vivo, futhi i-avermectin inobudlelwane obuphansi kuphela beziteshi ze-mammalian ligand-chloride.Lo mkhiqizo awukwazi ukungena kumgoqo wegazi nobuchopho bomuntu.I-Onchocerciasis kanye ne-strongyloidiasis kanye ne-hookworm, i-ascaris, i-Trichuris trichiura, kanye nezifo ze-Enterobius vermicularis.
Ukusebenzisa
I-Ivermectin imithi esetshenziselwa ukwelapha izinhlobo eziningi ze-parasite infestations.I-Ivermectin isetshenziselwa ukwelapha izifo zezilwane ezibangelwa ama-roundworms nama-ectoparasites.
I-Ivermectin ijwayele ukusetshenziselwa ukulawula izikelemu ze-parasitic ku-gastrointestinal tract of ruminant.Lezi zinambuzane zivame ukungena esilwaneni lapho sidla ukudla, zidlule emathunjini, bese zihlala futhi zivuthwe emathunjini, ngemva kwalokho zikhiqize amaqanda ashiya isilwane ngendle yaso futhi angahlasela amadlelo amasha.I-Ivermectin iyasebenza ekubulaleni ezinye, kodwa hhayi zonke, zalezi zimuncagazi.Ezinjeni isetshenziswa njalo njenge-prophylaxis ngokumelene nezikelemu zenhliziyo.
Emithi yezilwane, isetshenziselwa ukuvimbela nokwelapha isifo senhliziyo kanye ne-acariasis, phakathi kwezinye izinkomba.Ingathathwa ngomlomo noma ifakwe esikhumbeni ukuze kuhlaselwe izifo zangaphandle.Ivermectin kabanzi for nematodes emathunjini, lungworms, futhi arthropods yisinanakazana izinkomo, izimvu, amahhashi, nezingulube, nematodes emathunjini in izinja, izimbuzane indlebe, Sarcoptes scabiei, filariae inhliziyo, futhi microfilariae, kanye nematodes emathunjini emathunjini kanye nematodes emathunjini.
Amalungiselelo
Umjovo we-Ivermectin1% ,2% ,3.4%, 4%;
Ivermectin isixazululo ngomlomo 0.08%, 0.8%, 0.2%;
Ivermectin premix;
Ivermectin bolus;
Ivermectin thela-on isixazululo 0.5% ,1% ;
I-Ivermectin gel 0.4%
Unjiniyela ochwepheshe ozinikele ukukuqondisa
Ngokwezidingo zakho zangempela, khetha izinqubo zokuklama nezokuhlela ezinengqondo kakhulu