Ivermectin
Ivermectin
Ivermectin ngumgubo omhlophe wekristale, ongenavumba.Inyibilika ngokukhululekileyo kwi-methanol, i-ethanol, i-acetone, i-ethyl acetate, ayinyibiliki ngokuthe ngqo emanzini, kunye ne-hygroscopic kancinane.Ivermectin i semisynthetic macrolide multi-component antibiotic, equlathe ikakhulu ivermectin B1 (Bla + B1b) umxholo ongekho ngaphantsi kwama-95%, apho umxholo Bla ongekho ngaphantsi kwama-85%.
Umgaqo Wezonyango
Ivermectin inempembelelo ekhethiweyo yokuthintela, ngokuzibophelela kubudlelwane obuphezulu bemijelo yechloride kunye ne-glutamate njengevalve kwiiseli zemithambo-luvo kunye neeseli zezihlunu zezilwanyana ezingenaspinless, nto leyo ekhokelela ekungeneni kwenwebu zeseli kwi-ion ye-chloride, ibangela i-hyperpolarization yeeseli zemithambo-luvo. okanye iiseli zezihlunu, kwaye ibangela ukukhubazeka okanye ukufa kwee-parasites.Ikwasebenzisana ne-chloride channels zezinye iivalve ze-ligand, ezifana ne-neurotransmitter g-aminobutyric acid (GABA).Ukukhethwa kwale mveliso kungenxa yokuba ezinye izilwanyana ezincelisayo azinayo i-glutamate-chloride channels kwi-vivo, kwaye i-avermectin inobudlelwane obuphantsi kuphela kwiitshaneli ze-mammalian ligand-chloride.Le mveliso ayikwazi ukungena kumqobo wegazi-ingqondo yomntu.I-Onchocerciasis kunye ne-strongyloidiasis kunye ne-hookworm, i-ascaris, i-Trichuris trichiura, kunye nosulelo lwe-Enterobius vermicularis.
Ukusebenzisa
Ivermectin liyeza elisetyenziselwa ukunyanga iintlobo ezininzi ze-parasite infestations.Ivermectin isetyenziselwa ukunyanga izilwanyana izifo ezibangelwa yi roundworms kunye ectoparasites.
Ivermectin isetyenziswa rhoqo ukulawula iintshulube parasitic kwi phecana emathunjini izilwanyana ruminant.Ezi zifunxi-gazi zidla ngokungena esilwanyaneni xa sisatya, zidlule emathunjini, zize zihlale kwaye zivuthwe emathunjini, emva koko zivelise amaqanda ashiya isilwanyana ngendle yaso kwaye anokuhlasela amadlelo amatsha.I-Ivermectin iyasebenza ekubulaleni ezinye, kodwa hayi zonke, kwezi zifunxi-gazi.Kwizinja isetyenziswa rhoqo njengeprophylaxis ngokuchasene neheartworm.
Kwiyeza lezilwanyana, isetyenziselwa ukuthintela kunye nokunyanga i-heartworm kunye ne-acariasis, phakathi kwezinye izibonakaliso.Inokuthi ithathwe ngomlomo okanye isetyenziswe esikhumbeni ngenxa yokuhlaselwa kwangaphandle.Ivermectin isetyenziswa ngokubanzi nematodes emathunjini, lungworms, kunye parasitic arthropods ezinkomeni, iigusha, amahashe, neehagu, nematodes intestinal ezinjeni, imites indlebe, Sarcoptes scabiei, intliziyo filariae, kunye microfilariae, kunye nematodes emathunjini kunye nematodes emathunjini.
Amalungiselelo
Inaliti ye-Ivermectin1% ,2% ,3.4%, 4%;
Ivermectin isisombululo somlomo 0.08%, 0.8%, 0.2%;
Ivermectin premix;
Ivermectin bolus;
Ivermectin yokugalela isisombululo 0.5% ,1% ;
Ivermectin gel 0.4%
Injineli yobuchwephesha obuchwepheshile ezinikele ukukukhokela
Ngokweemfuno zakho zokwenyani, khetha eyona ndlela ifanelekileyo yoyilo kunye neenkqubo zokucwangcisa