Anti- PIVKA -II Antibody, Mouse Monoclonal

Selelekela

HloekisoProtein A/G affinity kholomoIsotypeIgG1 kappaHost SpeciesMouseAntigen SpeciesHumanApplicationImmunochromatography (IC)/Chemiluminescent Immunoassay (CLIA)

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Lintlha tse akaretsang

Protheine e Hlahetsoeng ke Vitamin K Absence kapa Antagonist-II (PIVKA-II), e tsejoang hape e le Des-γ-carboxy-prothrombin (DCP), ke mofuta o sa tloaelehang oa prothrombin.Ka tloaelo, masala a prothrombin's 10 glutamic acid (Glu) sebakeng sa γ-carboxyglutamic acid (Gla) maemong a 6, 7, 14, 16, 19, 20,25, 26, 29 le 32 ke γ-carboxylated ho Gla by vithamine. -K e itšetlehileng ka γ- glutamyl carboxylase sebeteng ebe e kenngoa ka har'a plasma.Ho bakuli ba nang le hepatocellular carcinoma (HCC), γ-carboxylation ea prothrombin e senyeha e le hore PIVKA-II e thehoe sebakeng sa prothrombin.PIVKA-II e nkoa e le biomarker e sebetsang hantle bakeng sa HCC.

Thepa

Keletso ea para CLIA (Tlhapa-Tshireletso):

1E5 ~ 1D6

1E5 ~ 1E6

Bohloeki >95%, e khethoa ke SDS-PAGE
Tlhahiso ea Buffer 20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH7.4
Polokelo E boloke tlas'a maemo a nyopa ho -20 ℃ ho -80 ℃ ha e amoheloa.Bakeng sa polokelo ea nako e telele, ka kopo aliquot 'me u e boloke.Qoba ho ba le serame khafetsa le ho qhibiliha.

Tlhahlobo ea Papiso

Lintlha tsa Odara

Lebitso la Sehlahiswa Katse.Che ID ea Clone
PIVKA- AB0009-1 1F4
AB0009-2 1E5
AB0009-3 1D6
AB0009-4 1E6

Tlhokomeliso: e ka etsa palo e ikhethileng ho latela tlhoko ea hau.

Litlhaloso

1.Matsueda K , Yamamoto H , Yoshida Y , et al.Hepatoid carcinoma ea manyeme a hlahisang protheine e bakoang ke ho ba sieo ha vithamine K kapa mohanyetsi oa II (PIVKA-II) le α-fetoprotein (AFP) [J].Journal of Gastroenterology, 2006, 41(10):1011-1019.

2.Viggiani, Valentina, Palombi, 等.Protheine e bakoang ke ho ba sieo ha vithamine K kapa mohanyetsi-II (PIVKA-II) e eketsehile ka ho khetheha ho bakuli ba Italy ba hepatocellular carcinoma.[J].Scandinavian Journal of Gastroenterology, 2016.

3.Simundic AM .Litlhahiso tse sebetsang bakeng sa tlhahlobo ea lipalo-palo le tlhahiso ea data ho Biochemia Medica Journal[J].Biochemia Medica, 2012, 22 (1).

4.Tartaglione S , Pecorella I , Zarrillo SR , et al.Protheine e Hlahetsoeng ke Vitamin K Absence II (PIVKA-II) e le serological biomarker e ka bang teng mofetšeng oa pancreatic: thuto ea sefofane[J].Biochemia Medica, 2019, 29(2).


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