Pharmacodynamics

Amoxicillin ke lithibela-mafu tsa β-lactam tse nang le phello e matla ea antibacterial.Ts'ebetso ea antibacterial le antibacterial ha e le hantle e tšoana le ea ampicillin, 'me tšebetso ea antibacterial khahlano le libaktheria tse ngata tsa Gram-positive e fokola hanyane ho feta ea penicillin.E na le phello e matla ho libaktheria tsa Gram-negative tse kang Escherichia coli, Proteus, Salmonella, Haemophilus, Brucella le Pasteurella, empa libaktheria tsena li na le bothata ba ho hanyetsa lithethefatsi.Ha e ts'oaroe ke Pseudomonas aeruginosa.Hobane ho monya ha eona ho liphoofolo tse monogastric ho betere ho feta ampicillin mme khatello ea mali ea eona e phahame, e na le phello e betere ea kalafo ho ts'oaetso ea systemic.E loketse mafu a tsamaiso a kang tsamaiso ea ho hema, tsamaiso ea moroto, letlalo le lisele tse bonolo tse bakoang ke libaktheria tse nang le kutloelo-bohloko.

Pharmacokinetics

Amoxicillin e tsitsitse ho gastric acid, 'me 74% ho isa ho 92% e monngoa ka mor'a ho tsamaisoa ka molomo ho liphoofolo tse nang le monogastric.Lintho tse ka har'a pampitšana ea mala li ama sekhahla sa ho monya, empa eseng tekanyo ea ho monya, kahoo e ka tsamaisoa ka phepelo e tsoakiloeng.Kamora ho nka tekanyetso e tšoanang ka molomo, khatello ea serum ea amoxicillin e phahame ka makhetlo a 1.5 ho isa ho a 3 ho feta ea ampicillin.

(1) Motsoako oa sehlahisoa sena le li-aminoglycosides li ka eketsa bongata ba libaktheria, ho bonts'a phello ea synergistic.(2) Li-bacteriostatic agents tse sebetsang ka potlako tse kang macrolides, tetracyclines le amide alcohols li kena-kenana le phello ea bactericidal ea sehlahisoa sena, 'me ha lia lokela ho sebelisoa hammoho.

lithibela-mafu tsa β-lactam.Bakeng sa kalafo ea mafu a amoxicillin a ts'oaetsoang ke gram-positive le gram-negative likhoho.

E ipapisitse le sehlahisoa sena.Tsamaiso ea molomo: tekanyo e le 'ngoe, ka 1kg boima ba' mele, khoho 0.2-0.3g, habeli ka letsatsi, ka matsatsi a 5;seno se tsoakiloeng: ka 1L ea metsi, khoho 0.6g, ka matsatsi a 3-5.

E na le phello e matla ea ho kena-kenana le limela tse tloaelehileng tsa pampitšana ea gastrointestinal.

(1) E thibetsoe ho behella likhoho nakong ea ho behela.

(2) Tšoaetso ea baktheria ea gram-positive e hanyetsanang le penicillin ha ea lokela ho sebelisoa.

(3) Kabo ea hajoale le ts'ebeliso.

Matsatsi a 7 bakeng sa likhoho.

shading, paballo e tiisitsoeng