Ivermectin
Ivermectin
Ivermectin ichena crystalline poda, isinganhuhwi.Inonyungudika zvakasununguka mumethanol, ethanol, acetone, ethyl acetate, isinganyunguriki mumvura, uye zvishoma hygroscopic.Ivermectin is semisynthetic macrolide multi-component antibiotic, iyo inonyanya kuve ne ivermectin B1 (Bla + B1b) yezvinyorwa zvisingasviki 95%, izvo Bla zvirimo zvisingasviki 85%.
Nheyo Yomushonga
Ivermectin ine inosarudzika inhibitory mhedzisiro, nekusunga kune yakakwira affinity yechloride migero ine glutamate sevharuvhu mumasero etsinga uye mhasuru masero emhuka dzisina spinless, izvo zvinotungamira mukusakwana kwepermeability ye cell membranes kune chloride ion, inokonzera hyperpolarization yemasero etsinga. kana masero emhasuru, uye zvinokonzera kuoma mitezo kana kufa kwezvipembenene.Iyo zvakare inopindirana ne chloride migero yemamwe ligand mavharuvhu, akadai neurotransmitter g-aminobutyric acid (GABA).Kusarudzwa kwechigadzirwa ichi imhaka yekuti dzimwe mhuka dzinoyamwisa hadzina glutamate-chloride migero mu vivo, uye avermectin inongova nehukama hwakaderera hwemammalian ligand-chloride chiteshi.Ichi chigadzirwa hachigone kupinda muropa remunhu-uropi chipingamupinyi.Onchocerciasis uye strongyloidiasis uye hookworm, ascaris, Trichuris trichiura, uye Enterobius vermicularis zvirwere.
Kushandisa
Ivermectin mushonga unoshandiswa kurapa marudzi mazhinji emaparasite infestations.Ivermectin inoshandiswa kurapa mhuka zvirwere zvinokonzerwa neroundworms uye ectoparasites.
Ivermectin inogara ichishandiswa kudzora makonye eparasitic mudumbu remhuka dzinotyisa.Zvipembenene izvi zvinowanzopinda mumhuka kana ichifura, ichipfuura ura, uye inogara uye yakakura muura, mushure mezvo inobudisa mazai anosiya mhuka kuburikidza nemarara ayo uye inogona kukanganisa mafuro matsva.Ivermectin inoshanda mukuuraya zvimwe, asi kwete zvese, zvezvipembenene izvi.Mumbwa inogara ichishandiswa seprophylaxis kurwisa heartworm.
Mukurapa kwezvipfuyo, inoshandiswa kudzivirira nekurapa heartworm uye acariasis, pakati pezvimwe zviratidzo.Inogona kutorwa nemuromo kana kushandiswa paganda rekunze kwekunze.Ivermectin inoshandiswa zvakanyanya kuita gastrointestinal nematodes, lungworms, uye parasitic arthropods mumombe, makwai, mabhiza, uye nguruve, intestinal nematodes mumbwa, ear mites, Sarcoptes scabiei, heart filariae, uye microfilariae, uye gastrointestinal nematodes nematodes.
Gadziriro
Ivermectin jekiseni1% ,2% ,3.4%, 4%;
Ivermectin oral solution 0.08%, 0.8%, 0.2%;
Ivermectin premix;
Ivermectin bolus;
Ivermectin kudira-pane mhinduro 0.5% ,1% ;
Ivermectin gel 0.4%
Professional tekinoroji mainjiniya akazvipira kukutungamira
Zvinoenderana nezvido zvako chaizvo, sarudza inonzwisisika yakazara dhizaini uye kuronga maitiro