Anti- PIVKA -II Antibody, Iole Monoclonal
Fa'amatalaga Lautele
Polotini Fa'aosoina e le Vitamin K Absence po'o le Antagonist-II (PIVKA-II), e ta'ua foi o le Des-γ-carboxy-prothrombin (DCP), ose ituaiga fa'aletonu ole prothrombin.E masani lava, o le prothrombin's 10 glutamic acid toega (Glu) i le γ-carboxyglutamic acid (Gla) domain i tulaga 6, 7, 14, 16, 19, 20,25, 26, 29 ma le 32 o le γ-carboxylated i Gla e vitamini. -K fa'alagolago γ- glutamyl carboxylase i le ate ona fa'alilo lea i le plasma.I tagata gasegase e maua i le hepatocellular carcinoma (HCC), o le γ-carboxylation o le prothrombin ua faʻaleagaina ina ia faia ai le PIVKA-II nai lo le prothrombin.O le PIVKA-II o lo'o manatu o se biomarker lelei fa'apitoa mo HCC.
Meatotino
| Fautuaga paga | CLIA (Pu'e-Su'eina): 1E5 ~ 1D6 1E5 ~ 1E6 |
| mama | >95%, fuafuaina e le SDS-PAGE |
| Fausia Fa'amau | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH7.4 |
| Teuina | Teuina i lalo o tulaga faʻamaʻi ile -20 ℃ i le -80 ℃ pe a maua.Mo le teuina umi, faamolemole aliquot ma teu.Aloese mai ta'amilosaga fa'aaisa ma liusua faifai pea. |
Iloiloga Faatusatusa
Fa'amatalaga oka
| Igoa Oloa | Pusi.leai | Clone ID |
| PIVKA-Ⅱ | AB0009-1 | 1F4 |
| AB0009-2 | 1E5 | |
| AB0009-3 | 1D6 | |
| AB0009-4 | 1E6 |
Fa'aaliga: e mafai ona fa'avasega le aofa'i mo lou mana'oga.
Upusii
1.Matsueda K , Yamamoto H , Yoshida Y , et al.Hepatoid carcinoma o le pancreas e gaosia ai le polotini e mafua mai i le leai o se vaitamini K poʻo le faʻalavelave II (PIVKA-II) ma le α-fetoprotein (AFP) [J].Journal of Gastroenterology, 2006, 41 (10): 1011-1019.
2.Viggiani, Valentina, Palombi,等.Polotini fa'aosoina e le vaitamini K toesea po'o le antagonist-II (PIVKA-II) fa'atuputeleina fa'atuputeleina i Italia hepatocellular carcinoma ma'i.[J].Scandinavian Journal of Gastroenterology, 2016.
3.Simundic AM .Fautuaga fa'ata'ita'i mo su'esu'ega fa'afuainumera ma fa'amatalaga fa'amatalaga i le Biochemia Medica journal[J].Biochemia Medica, 2012, 22(1).
4.Tartaglione S, Pecorella I, Zarrillo SR, et al.Polotini Fa'aosoina e le Vitamin K Absence II (PIVKA-II) e avea o se faʻailoga faʻapitoa faʻapitoa i le kanesa pancreatic: o se suʻesuʻega pailate [J].Biochemia Medica, 2019, 29(2).
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