Tiamulin Hydrogen Fumarate
Tiamulin hydrogen fumarate
Tiamulin hydrogen fumarate ikomoka kuri pleuromutiline, irashobora gukoreshwa mubuvuzi bwamatungo cyane cyane ku ngurube n’inkoko.Ni mikorobe ya diterpene ifite imiti ya pleuromutiline isa na valnemuline.
Tiamuline hydrogen fumarate yera cyangwa ifu yera ya kirisiti yera, idafite impumuro nziza kandi itaryoshye.Irashobora gushonga byoroshye muri methanol cyangwa Ethanol, gushonga mumazi, gushonga gake muri acetone, kandi hafi ya erega muri hexane.
Uburyo bwibikorwa nibiranga
Iki gicuruzwa ni antibiyotike ya bacteriostatike, ariko kandi igira ingaruka kuri bagiteri yica bagiteri yunvikana cyane.Uburyo bwa antibacterial bwibikorwa ni ukubuza intungamubiri za poroteyine za bagiteri guhuza na 50s subunit ya bagiteri ribosome.
Tiamulin hydrogen fumarate ifite ibikorwa byiza bya antibacterial kurwanya cocci zitandukanye za Gram-positif, harimo staphylococci na streptococci nyinshi (usibye itsinda D streptococci) hamwe na mycoplasma zitandukanye hamwe na spirochette.Nyamara, ibikorwa bya antibacterial kurwanya bagiteri zimwe na zimwe mbi birakomeye cyane, usibye ubwoko bwa Haemophilus hamwe na E. coli na Klebsiella.
Tiamulin hydrogen fumarate iroroshye kwinjizwa nyuma yubuyobozi bwo munwa mu ngurube.Hafi ya 85% yumuti umwe urashiramo, kandi kwibumbira hejuru bibaho mumasaha 2 kugeza 4.Ikwirakwizwa cyane mu mubiri, hamwe cyane cyane mu bihaha.Tiamulin hydrogen fumarate ihindurwamo umubiri mumubiri wa metabolite 20, zimwe zifite umutuzo wa antibacterial.Hafi ya 30% ya metabolite iramburwa mu nkari naho ibisigaye bigacibwa mu mwanda.
Ikoreshwa
Tiamuline hydrogen fumarate ikoreshwa mu kuvura umusonga w’ingurube iterwa na Actinobacillus pleuropneumoniae hamwe n’amaraso y’ingurube yatewe na Treponema hyodysenteriae.Nkibiryo byongera imiti yingurube birashobora kongera ibiro.Ifite kandi akamaro ko kurwanya indwara z'ubuhumekero zidakira mu nkoko, mycoplasma hyopneumonia, na synovitis ya staphylococcal mu nkoko.
Ibirimo
≥ 98%
Ibisobanuro
USP42 / EP10
Gupakira
25kg / ikarito yingoma
Imyiteguro
10%, 45% 80% Tiamulin hydrogen fumarate premix / ifu ya elegitoronike
Inzobere mu bya tekinike yabigize umwuga yitangiye kukuyobora
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