Anti- PIVKA -II Antibody, Monoclonal Mouse
ʻIke Nui
ʻO ka Protein i hoʻokomo ʻia e ka Vitamin K Absence a i ʻole Antagonist-II (PIVKA-II), i ʻike ʻia ʻo Des-γ-carboxy-prothrombin (DCP), he ʻano ʻano like ʻole o ka prothrombin.ʻO ka mea maʻamau, ʻo ka prothrombin's 10 glutamic acid residues (Glu) i loko o ka γ-carboxyglutamic acid (Gla) domain ma nā kūlana 6, 7, 14, 16, 19, 20,25, 26, 29 a me 32 he γ-carboxylated iā Gla e ka vitamina. -K hilinaʻi γ- glutamyl carboxylase i loko o ke ake a laila huna ʻia i loko o ka plasma.I nā poʻe maʻi me ka maʻi hepatocellular carcinoma (HCC), ua hoʻopilikia ʻia ka γ-carboxylation o ka prothrombin no laila ua hoʻokumu ʻia ka PIVKA-II ma kahi o ka prothrombin.Manaʻo ʻia ʻo PIVKA-II he biomarker kūpono no ka HCC.
Waiwai
| Manaʻo Pair | CLIA (Hopu-Hopu): 1E5 ~ 1D6 1E5 ~ 1E6 |
| Maemae | >95%, hoʻoholo ʻia e SDS-PAGE |
| Hoʻohāpai ʻia | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH7.4 |
| Waihona | E mālama iā ia ma lalo o nā kūlana sterile ma -20 ℃ a -80 ℃ ma ka loaʻa ʻana.No ka mālama lōʻihi, e ʻoluʻolu e aliquot a mālama.E hōʻalo i nā pōʻai maloʻo a hoʻolulu. |
Nānā Hoʻohālikelike
ʻIke Kauoha
| inoa mea kūʻai | Cat.ʻAʻole | Klone ID |
| PIVKA-Ⅱ | AB0009-1 | 1F4 |
| AB0009-2 | 1E5 | |
| AB0009-3 | 1D6 | |
| AB0009-4 | 1E6 |
'Ōlelo Aʻo: hiki ke hoʻololi i ka nui o kāu pono.
Kuhikuhi
1.Matsueda K , Yamamoto H , Yoshida Y , et al.ʻO ka maʻi hepatoid o ka pancreas e hana ana i ka protein i hoʻoulu ʻia e ka huaʻa K a i ʻole antagonist II (PIVKA-II) a me ka α-fetoprotein (AFP) [J].Nūpepa o Gastroenterology, 2006, 41 (10): 1011-1019.
2.Viggiani, Valentina, Palombi, 等.ʻO ka protein i hoʻoulu ʻia e ka ʻole o ka huaora K a i ʻole antagonist-II (PIVKA-II) i hoʻonui nui ʻia i nā maʻi maʻi hepatocellular carcinoma Italia.[J].Scandinavian Journal of Gastroenterology, 2016.
3.Simundic AM .Nā ʻōlelo aʻoaʻo hoʻomaʻamaʻa no ka ʻikepili helu a me ka hōʻike ʻana i ka ʻikepili ma ka puke pai Biochemia Medica [J].Biochemia Medica, 2012, 22(1).
4.Tartaglione S, Pecorella I, Zarrillo SR, et al.Hoʻokomo ʻia ka Protein e ka Vitamin K Absence II (PIVKA-II) ma ke ʻano he biomarker serological i ka maʻi maʻi pancreatic: kahi noiʻi pilote [J].Biochemia Medica, 2019, 29(2).
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